Introduction 

Malaria is a parasitic protozoan disease transmitted to humans through the bite of an infected female Anopheles mosquito. The malaria parasite enters the liver cells and undergoes parasitism and reproduction within them. Upon maturation, it invades red blood cells for further multiplication, eventually causing these cells to rupture en masse, leading to the onset of the disease, which poses a significant threat to human health. The World Health Organization (WHO) has listed malaria alongside tuberculosis and AIDS as the three most dangerous infectious diseases affecting humanity. During the period from 2020 to 2021, the number of malaria cases continued to rise, albeit at a slower rate than in the preceding year from 2019 to 2020. In 2021, the global total of malaria cases reached 247 million, up from 245 million in 2020 and 232 million in 2019. The number of global malaria deaths remained relatively stable in 2021, with 619,000 fatalities reported, compared to 625,000 in 2020 and 568,000 in 2019.Currently, according to WHO statistics, there are three primary effective measures for malaria control: Insecticide-treated bed nets (ITNs), Rapid Diagnostic Test Kits (RDTs), and Artemisinin-based Combination Therapies (ACTs). Therefore, rapid diagnosis plays a critically important role in overall malaria control efforts.

There are 5 Plasmodium parasite species that cause malaria in humans and 2 of these species – P. falciparum and P. vivax – pose the greatest threat. P. falciparum is the deadliest malaria parasite and the most prevalent on the African continent. P. vivax is the dominant malaria parasite in most countries outside of sub-Saharan Africa. The other malaria species which can infect humans are P. malariae, P. ovale and P. knowlesi. Therefore, the utmost importance lies in the rapid identification and control of Plasmodium falciparum and Plasmodium vivax.

This kit is designed with specific primers and probes targeting the conserved region of Plasmodium species, generating fluorescence signals on a constant temperature nucleic acid amplification instrument. By employing POCT detection, it realizes qualitative and genotypic identification of Plasmodium at the nucleic acid level.

Test Items